Article
PCR-based methods for the detection of L1014 kdr mutation in Anopheles culicifacies sensu lato.
Malaria journal - 14 Jul 2009
Singh Om P, Bali Prerna, Hemingway Janet, Subbarao Sarala K, Dash Aditya P, Adak Tridibes
Abstract excerpt
BACKGROUND: Anopheles culicifacies s.l., a major malaria vector in India, has developed widespread resistance to DDT and is becoming resistant to pyrethroids-the only insecticide class recommended for the impregnation of bed nets. Knock-down resistance due to a point mutation in the voltage gated sodium channel at L1014 residue (kdr) is a common mechanism of resistance to DDT and pyrethroids. The selection of...
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