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Germ-cell hyaluronidases: their roles in sperm function

21 Mar 2011

Abstract excerpt

Hyaluronidases (hyases) are a family of enzymes that catalyse the breakdown of hyaluronic acid (HA), which is abundant in the extracellular matrix. Two unlinked gene clusters encode these six proteins: three each in the somatic (or ubiquitous) acid-active subgroup and the neutral-active germ-cell subgroup. This review analyses the data on the expression and role of hyases in gamete biology and fertilization,...

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PMID: 21418239
DOI: 10.1111/j.1365-2605.2010.01138.x

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