Article
HMGA Interactome: new insights from phage display technology.
Biochemistry - 3 May 2011
Malini Erika, Maurizio Elisa, Bembich Sara, Sgarra Riccardo, Edomi Paolo, Manfioletti Guidalberto
Abstract excerpt
High mobility group A proteins (HMGA1 and HMGA2) are architectural factors involved in chromatin remodelling and regulation of gene expression. HMGA are highly expressed during embryogenesis and in cancer cells and are involved in development and cell differentiation as well as cancer formation and progression. These factors, by binding to DNA and interacting with other nuclear proteins, can organize...
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