Article
Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.
Molecular genetics and metabolism - 1 Jun 2011
Merino Diana M, Johnston Holly, Clarke Shannon, Roke Kaitlin, Nielsen Daiva, Badawi Alaa, El-Sohemy Ahmed, Ma David W L, Mutch David M
Abstract excerpt
Recent evidence indicates that genetic variation in fatty acid desaturases 1 and 2 (FADS1 and FADS2) is associated with changes in plasma fatty acid profiles; however, the association with altered desaturase activity has not been examined in different ethnic populations. The present study examined whether genetic variation in the FADS gene cluster regulates desaturase activity in two populations of young Canadian...
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