Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and genomic analysis of serotype 3 Sabin poliovirus vaccine produced in MRC-5 cell substrate.

Journal of medical virology - 1 May 2011

Alirezaie Behnam, Taqavian Mohammad, Aghaiypour Khosrow, Esna-Ashari Fatemeh, Shafyi Abbas

Abstract excerpt

The cell substrate has a pivotal role in live virus vaccines production. It is necessary to evaluate the effects of the cell substrate on the properties of the propagated viruses, especially in the case of viruses which are unstable genetically such as polioviruses, by monitoring the molecular and phenotypical characteristics of harvested viruses. To investigate the presence/absence of mutation(s), the near...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Culture Techniques
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Mutation

Share to Poliovirus

Share to RNA, Viral

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 21412797
DOI: 10.1002/jmv.21804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and genomic analysis of serotype 3 Sabin poliovirus vaccine produced in MRC-5 cell substrate.PMID 21412797Read ↗

Microevolution of type 3 Sabin strain of poliovirus in cell cultures and its implications for oral poliovirus vaccine quality control.Semantic proximity Read ↗

Overview of measles and mumps vaccine: origin, present, and future of vaccine productionSemantic proximity Read ↗

Correlation of mutations and recombination with growth kinetics of poliovirus vaccine strains.Semantic proximity Read ↗

Microevolution of Sabin 1 strain in vitro and genetic stability of oral poliovirus vaccine.Semantic proximity Read ↗

New Strains Intended for the Production of Inactivated Polio Vaccine at Low-Containment After EradicationSemantic proximity Read ↗

Rational design of genetically stable, live-attenuated poliovirus vaccines of all three serotypes: relevance to poliomyelitis eradication.Semantic proximity Read ↗

Methods to Monitor Molecular Consistency of Oral Polio Vaccine.Semantic proximity Read ↗

Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End GameSemantic proximity Read ↗

Poliovirus-nonsusceptible Vero cell line for the World Health Organization global action planSemantic proximity Read ↗

Genetic and Phenotypic Characterization of Manufacturing Seeds for a Tetravalent Dengue Vaccine (DENVax)Semantic proximity Read ↗

Developing genetically stable live-attenuated vaccine candidates against type 1 and 3 poliovirusSemantic proximity Read ↗

Analysis of the accumulation of mutants in Sabin attenuated polio vaccine viruses passaged in Vero cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.