Article
Plasminogen activator activities of equimolar complexes of streptokinase with variant recombinant plasminogens.
Biochemistry - 10 Apr 1990
Davidson D J, Higgins D L, Castellino F J
Abstract excerpt
The steady-state kinetic characteristics of the amidolytic and plasminogen activator activities of equimolar streptokinase (SK)-human plasminogen (HPg) and SK-human plasmin (HPm) complexes have been determined, exploiting the generation and use of cleavage site resistant mutants of HPg to stabili...
Topics
- Amidohydrolases
- Base Sequence
- DNA
- Fibrinolysin
- Humans
- Kinetics
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
- Plasminogen
- Plasminogen Activators
- Recombinant Proteins
- Streptokinase
