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Article

Plasminogen activator activities of equimolar complexes of streptokinase with variant recombinant plasminogens.

Biochemistry - 10 Apr 1990

Davidson D J, Higgins D L, Castellino F J

Abstract excerpt

The steady-state kinetic characteristics of the amidolytic and plasminogen activator activities of equimolar streptokinase (SK)-human plasminogen (HPg) and SK-human plasmin (HPm) complexes have been determined, exploiting the generation and use of cleavage site resistant mutants of HPg to stabilize plasminogen within the complex. Whereas amidolytic kinetic constants for equimolar complexes of SK with the...

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PMID: 2141279
DOI: 10.1021/bi00466a023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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