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BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer.

Breast cancer research and treatment - 1 Jun 2011

Wong Michelle W, Nordfors Cecilia, Mossman David, Pecenpetelovska Gordana, Avery-Kiejda Kelly A, Talseth-Palmer Bente, Bowden Nikola A, Scott Rodney J

Abstract excerpt

Mutations in the recognized breast cancer susceptibility genes BRCA1, BRCA2, TP53, ATM, and CHEK2 account for approximately 20% of hereditary breast cancer. This raises the possibility that mutations in other biologically relevant genes may be involved in genetic predisposition to breast cancer. In this study, BRIP1, PALB2, and RAD51C were sequenced for mutations as a result of previously being associated with...

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Source

Identifiers

PMID: 21409391
DOI: 10.1007/s10549-011-1443-0

Genes

PALB2
BRIP1
BRCA1
BRCA2
ATM
CHEK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer.PMID 21409391Read ↗

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