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Article

Cloning of non-human primates: the road "less traveled by"

1 Jan 2010

Abstract excerpt

Early studies on cloning of non-human primates by nuclear transfer utilized embryonic blastomeres from preimplantation embryos which resulted in the reproducible birth of live offspring. Soon after, the focus shifted to employing somatic cells as a source of donor nuclei (somatic cell nuclear transfer, SCNT). However, initial efforts were plagued with inefficient nuclear reprogramming and poor embryonic...

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PMID: 21404187
DOI: 10.1387/ijdb.103196ms

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