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Article

A comparative approach to somatic cell nuclear transfer in the rhesus monkey

22 Jun 2006

Abstract excerpt

BACKGROUND: Despite the potential utility of primate somatic cell nuclear transfer (SCNT) to biomedical research and to the production of autologous embryonic stem (ES) cells for cell- or tissue-based therapy, a reliable method for SCNT is not yet available. Employing the rhesus monkey as a clinically relevant animal model, we have compared a conventional electrofusion method for SCNT with a one-step...

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PMID: 16793991
DOI: 10.1093/humrep/del216

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