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Article

The role of Escherichia coli UvrB in nucleotide excision repair.

The Journal of biological chemistry - 5 May 1990

Seeley T W, Grossman L

Abstract excerpt

The role of UvrB in determining the nucleotide dependence of Escherichia coli excision repair has been investigated. The mutation of lysine 45 in the ATPase motif of UvrB to alanine leads to an acute defect in ATP hydrolysis and failure to support incision of UV-damaged DNA. This ATP hydrolysis activity is not required for interaction of UvrB with UvrA in solution, or for formation of a damage-independent...

Topics

Adenosine Triphosphatases
Alanine
Bacterial Proteins
DNA Damage
DNA Helicases
DNA Repair
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Kinetics
Lysine
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ribonucleotides

Ultraviolet Rays

Source

Identifiers

PMID: 2139658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2139658-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The role of Escherichia coli UvrB in nucleotide excision repair.PMID 2139658Read ↗

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