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Article

Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2011

Haas Blake E, Weissglas-Volkov Daphna, Aguilar-Salinas Carlos A, Nikkola Elina, Vergnes Laurent, Cruz-Bautista Ivette, Riba Laura, Stancakova Alena, Kuusisto Johanna, Soininen Pasi, Kangas Antti J, Ala-Korpela Mika, Tusie-Luna Teresa, Laakso Markku, Pajukanta Päivi

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies identified a variant rs7575840 in the apolipoprotein B (APOB) gene region as associated with low-density lipoprotein (LDL) cholesterol. However, the underlying functional mechanism of this variant, which resides 6.5 kb upstream of APOB, has remained unknown. Our objective was to investigate rs7575840 for association with refined apoB-containing lipid particles,...

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Source

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Identifiers

PMID: 21393584
DOI: 10.1161/ATVBAHA.111.224139
PMCID: PMC3081410

Genes

APOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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