Article
Association of GWAS-based candidate genes with HDL-cholesterol levels before and after bariatric surgery in the Swedish obese subjects study.
The Journal of clinical endocrinology and metabolism - 1 Jun 2011
Sarzynski Mark A, Jacobson Peter, Rankinen Tuomo, Carlsson Björn, Sjöström Lars, Carlsson Lena M S, Bouchard Claude
Abstract excerpt
CONTEXT AND OBJECTIVE: The magnitude of weight loss-induced high-density lipoprotein cholesterol (HDL-C) changes may depend on genetic factors. We examined the associations of eight candidate genes, identified by genome-wide association studies, with HDL-C at baseline and 10 yr after bariatric surgery in the Swedish Obese Subjects study. METHODS: Single-nucleotide polymorphisms (SNP) (n = 60) in the following...
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