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Article

Lipid disorders and mutations in the APOB gene.

Clinical chemistry - 1 Oct 2004

Whitfield Amanda J, Barrett P Hugh R, van Bockxmeer Frank M, Burnett John R

Abstract excerpt

BACKGROUND: Plasma lipoproteins are important determinants of atherosclerosis. Apolipoprotein (apo) B is a large, amphipathic glycoprotein that plays a central role in human lipoprotein metabolism. Two forms of apoB are produced from the APOB gene by a unique posttranscriptional editing process: apoB-48, which is required for chylomicron production in the small intestine, and apoB-100, required for VLDL...

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Source

Identifiers

PMID: 15308601
DOI: 10.1373/clinchem.2004.038026

Genes

APOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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