Article
Maraviroc is able to inhibit dual-R5 viruses in a dual/mixed HIV-1-infected patient.
The Journal of antimicrobial chemotherapy - 1 Apr 2011
Symons Jori, van Lelyveld Steven F L, Hoepelman Andy I M, van Ham Petra M, de Jong Dorien, Wensing Annemarie M J, Nijhuis Monique
Abstract excerpt
OBJECTIVES: Maraviroc is the first licensed chemokine co-receptor 5 (CCR5) co-receptor antagonist in clinical practice. It is currently being used in patients harbouring exclusively CCR5-tropic virus. The objective of the study was to investigate the impact of maraviroc on viruses with different co-receptor preferences in a patient with a dual/mixed (D/M) infection. METHODS: We present a case report of an HIV-1...
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