Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mu gem3 as a tool to investigate the influence of chromosome supercoiling on gene expression in Escherichia coli K12.

FEMS microbiology letters - 1 Jan 1990

Bianchi E, Ruberti I, Ghelardini P, Paolozzi L

Abstract excerpt

We have developed a rapid method to investigate the influence of chromosome supercoiling on gene expression in Escherichia coli K12. This method exploits the ability of the gem3 mutant of the bacteriophage Mu, even in the prophagic state in immune cells, to induce relaxation of the host chromosome. The experiments can thus be performed under physiological conditions, and without the use of the drugs. In theory,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Chromosomes, Bacterial
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to DNA, Superhelical

Share to Escherichia coli

Share to Gene Expression Regulation, Bacterial

Share to Mutation

Source

Identifiers

PMID: 2138991
DOI: 10.1016/0378-1097(90)90271-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mu gem3 as a tool to investigate the influence of chromosome supercoiling on gene expression in Escherichia coli K12.PMID 2138991Read ↗

Global changes in gene expression in Escherichia coli K12 induced by bacteriophage Mu Gem protein.Semantic proximity Read ↗

A spontaneous Escherichia coli K12 mutant which inhibits the excision-reintegration process of Mu gem2ts.Semantic proximity Read ↗

Genetic Approaches to Study the Interplay Between Transcription and Nucleoid-Associated Proteins in Escherichia coli.Semantic proximity Read ↗

Transcription-coupled hypernegative supercoiling of plasmid DNA by T7 RNA polymerase in Escherichia coli topoisomerase I-deficient strains.Semantic proximity Read ↗

Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU.Semantic proximity Read ↗

The bacteriophage Mu gem gene: a positive regulator of the C operon required for normal levels of late transcription.Semantic proximity Read ↗

Synchronous division induced in Escherichia coli K12 by phage Mu: analysis of DNA topology and gene expression during the cell cycle.Semantic proximity Read ↗

Surveying a supercoil domain by using the gamma delta resolution system in Salmonella typhimurium.Semantic proximity Read ↗

Influence of DNA supercoiling on cisplatin toxicity in Escherichia coli K-12.Semantic proximity Read ↗

Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli.Semantic proximity Read ↗

Chromosome rearrangements induced by recombinant coliphage lambda placMu.Semantic proximity Read ↗

Study of the ability of a DNA polymerase mutant E. coli K12 pol A1 for elimination of single-stranded breaks in DNA caused by methyl methanesulfonate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.