Article
Caspase recruitment domain 15 gene haplotypes in sarcoidosis.
Tissue antigens - 1 Apr 2011
Pabst S, Golebiewski M, Herms S, Karpushova A, Díaz-Lacava A, Walier M, Zimmer S, Cichon S, Wienker T F, Nöthen M M, Nickenig G, Meyer R, Skowasch D, Grohé C
Abstract excerpt
Sarcoidosis is a systematic granulomatous disorder. Genetic susceptibility could play a central role in the disease development and progression. In this study, we investigated whether caspase recruitment domain 15 (CARD15) gene haplotypes are associated with the onset or the clinical course of sarcoidosis. Three hundred Caucasian sarcoidosis patients and 381 matched controls were included. Eight haplotype-tagging...
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