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Article

Intertumor heterogeneity of non-small-cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics.

International journal of cancer - 1 Sept 2014

Tan Daniel S W, Camilleri-Broët Sophie, Tan Eng Huat, Alifano Marco, Lim Wan-Teck, Bobbio Antonio, Zhang Shenli, Ng Quan-Sing, Ang Mei-Kim, Iyer N Gopalakrishna, Takano Angela, Lim Kiat Hon, Régnard Jean-François, Tan Patrick, Broët Philippe

Abstract excerpt

Non-small-cell lung cancer (NSCLC) is a heterogeneous disease, with a burden of genomic alterations exceeding most other tumors. The goal of our study was to evaluate the frequencies of co-occurring mutations and copy-number aberrations (CNAs) within the same tumor and to evaluate their potential clinical impact. Mass-spectrometry based mutation profiling using a customized lung cancer panel evaluating 214...

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PMID: 24482041
DOI: 10.1002/ijc.28750

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EGFR
KRAS
MET
STK11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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