Article
Reduced left hemispheric white matter volume in twins with bipolar I disorder.
Biological psychiatry - 1 Nov 2003
Kieseppä Tuula, van Erp Theo G M, Haukka Jari, Partonen Timo, Cannon Tyrone D, Poutanen Veli-Pekka, Kaprio Jaakko, Lönnqvist Jouko
Abstract excerpt
BACKGROUND: Although the heritability of bipolar I disorder (BPI) is high, few magnetic resonance imaging (MRI) studies of siblings of bipolar patients exist. We performed MRI brain scans on a nationwide sample of twins with BPI, as well as on their co-twins and a demographically balanced sample of control twin subjects, to detect any structural alterations related to the disorder and to the increased genetic...
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