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Article

Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2009

Kojima Kanako, Kuramochi-Miyagawa Satomi, Chuma Shinichiro, Tanaka Takashi, Nakatsuji Norio, Kimura Tohru, Nakano Toru

Abstract excerpt

The mouse Piwi family proteins (MILI, MIWI and MIWI2) play pivotal roles in spermatogenesis through transcriptional and post-transcriptional gene regulation. To reveal the molecular functions of these proteins, we investigate the proteins that bind to MILI in adult mouse testes. We found that both MILI and MIWI bind to TDRD1/MTR-1, which is also an essential protein for spermatogenesis. Co-immunoprecipitation...

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Identifiers

PMID: 19735482
DOI: 10.1111/j.1365-2443.2009.01342.x

Genes

MTR
TDRD1

Provenance

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Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.PMID 19735482Read ↗

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