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Article

The link between mitochondrial DNA hypervariable segment I heteroplasmy and ageing among genetically unrelated Latvians.

Experimental gerontology - 1 Jul 2011

Pliss Liana, Brakmanis Andis, Ranka Renate, Elferts Didzis, Krumina Astrida, Baumanis Viesturs

Abstract excerpt

Various studies have demonstrated that mitochondrial DNA (mtDNA) heteroplasmy tends to increase with age and that the observed frequency of heteroplasmy among populations mostly depends on the way it is measured. Therefore, we investigated age-related association on the presence of mtDNA heteroplasmy within the hypervariable segment 1 (HVS-I) in a selected study group. The study group consisted of 300 maternally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21377516
DOI: 10.1016/j.exger.2011.02.016

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