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Linkage between mitochondrial genome alterations, telomere length and aging population

24 Mar 2017

Abstract excerpt

We studied telomere length (TL) and mitochondrial DNA (mtDNA) copy number variations in individuals from Latvian Caucasian population in different age groups. We showed a positive correlation between TL and mtDNA copy number in individuals of up to 90 years of age; however, this correlation was not observed in the 90-100 years age group. While TL shortened with age and mtDNA content decreased with increasing age,...

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Share to DNA Repair Mechanisms
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PMID: 28340313
DOI: 10.1080/24701394.2017.1303490

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