Article
A280V polymorphism in the histamine H3 receptor as a risk factor for migraine.
Archives of medical research - 1 Jan 2011
Millán-Guerrero Rebeca O, Baltazar-Rodríguez Luz M, Cárdenas-Rojas Martha I, Ramírez-Flores Mario, Isais-Millán Sara, Delgado-Enciso Ivan, Caballero-Hoyos Ramiro, Trujillo-Hernández Benjamín
Abstract excerpt
BACKGROUND AND AIMS: Activation of histamine H3 receptors blocks the release of peptides responsible for headache. Our objective was to investigate the association between the genotypes of A280V polymorphism in the H3 receptor and migraine risk. METHODS: We evaluated the frequency of the genotypes of A280V, polymorphism A280V and allelic variants of H3 receptor in 147 migraine patients and 186 healthy controls...
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