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Article

NS5A sequence heterogeneity of hepatitis C virus genotype 4a predicts clinical outcome of pegylated-interferon-ribavirin therapy in Egyptian patients.

Journal of clinical microbiology - 1 Dec 2012

El-Shamy Ahmed, Shoji Ikuo, El-Akel Wafaa, Bilasy Shymaa E, Deng Lin, El-Raziky Maissa, Jiang Da-peng, Esmat Gamal, Hotta Hak

Abstract excerpt

Hepatitis C virus genotype 4 (HCV-4) is the cause of approximately 20% of the 180 million cases of chronic hepatitis C in the world. HCV-4 infection is common in the Middle East and Africa, with an extraordinarily high prevalence in Egypt. Viral genetic polymorphisms, especially within core and NS5A regions, have been implicated in influencing the response to pegylated-interferon and ribavirin (PEG-IFN/RBV)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22993188
DOI: 10.1128/JCM.02109-12
PMCID: PMC3502985

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NS5A sequence heterogeneity of hepatitis C virus genotype 4a predicts clinical outcome of pegylated-interferon-ribavirin therapy in Egyptian patients.PMID 22993188Read ↗

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