Article
Truncated Rv2820c enhances mycobacterial virulence ex vivo and in vivo.
Microbial pathogenesis - 1 Jun 2011
Lam J T, Yuen K Y, Ho P L, Weng X H, Zhang W H, Chen S, Yam W C
Abstract excerpt
Three hypervirulent strains of Mycobacterium tuberculosis isolated from patients suffering from tuberculous meningitis were shown to grow more rapidly inside human macrophages in our previous study. In the current investigation, genomic polymorphisms in these hypervirulent strains were examined using microarray-based comparative genomic hybridization. Among the five genomic polymorphisms identified, two are...
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