Article
Comparison of the efficacies of amantadine treatment of swine-origin influenza virus A H1N1 and seasonal influenza H1N1 and H3N2 in Japan (2008-2009).
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Aug 2011
Miyachi Kiyomitsu, Watanabe Atushi, Iida Hiromasa, Hattori Haruki, Ukai Hiroshi, Takano Tsuruyo, Hankins Raleigh W
Abstract excerpt
Amantadine is not thought to be effective for the treatment of swine-origin influenza virus (S-OIV) based on an analysis of genetic sequences of the M2 protein. However, the actual clinical efficacy of amantadine has not been well documented. Here, we were able to compare the efficacies of amantadine and neuraminidase inhibitors. Subjects consisted of 428 patients, including 144 with seasonal influenza (flu)...
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