Article
Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Dec 2009
Kawai Naoki, Ikematsu Hideyuki, Hirotsu Nobuo, Maeda Tetsunari, Kawashima Takashi, Tanaka Osame, Yamauchi Satoshi, Kawamura Kenichi, Matsuura Shinro, Nishimura Mika, Iwaki Norio, Kashiwagi Seizaburo
Abstract excerpt
BACKGROUND: Influenza A virus subtype H1N1 with the H274Y mutation emerged and spread worldwide. However, the clinical effectiveness of the neuraminidase inhibitors, oseltamivir and zanamivir, has not been adequately reevaluated. METHODS: Data from 164 patients with H1N1 virus infection and 59 pa...
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