Article
Influenza A viruses of swine circulating in the United States during 2009-2014 are susceptible to neuraminidase inhibitors but show lineage-dependent resistance to adamantanes.
Antiviral research - 1 May 2015
Baranovich Tatiana, Bahl Justin, Marathe Bindumadhav M, Culhane Marie, Stigger-Rosser Evelyn, Darnell Daniel, Kaplan Bryan S, Lowe James F, Webby Richard J, Govorkova Elena A
Abstract excerpt
Antiviral drug susceptibility is one of the evaluation criteria of pandemic potential posed by an influenza virus. Influenza A viruses of swine (IAV-S) can play an important role in generating novel variants, yet limited information is available on the drug resistance profiles of IAV-S circulating in the U.S. Phenotypic analysis of the IAV-S isolated in the U.S. (2009-2011) (n=105) revealed normal inhibition by...
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