Article
Genetics of asthma: the University of Toronto Program. University of Toronto Genetics of Asthma Research Group.
American journal of respiratory and critical care medicine - 1 Oct 1997
Slutsky A S, Zamel N
Abstract excerpt
In 1991, we initiated a study to identify susceptibility gene(s) predisposing individuals to the development of asthma. Our strategy was to focus on the collection of inbred populations because (1) they are likely to exhibit greater homogeneity than outbred populations, potentially important in multigenic diseases, (2) there may be fewer genes explaining the asthma diathesis in families with a "founder effect,"...
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