Article
Vitamin D receptor (VDR) and group-specific component (GC, vitamin D-binding protein) polymorphisms in myopia.
Investigative ophthalmology & visual science - 1 Jun 2011
Mutti Donald O, Cooper Margaret E, Dragan Ecaterina, Jones-Jordan Lisa A, Bailey Melissa D, Marazita Mary L, Murray Jeffrey C, Zadnik Karla
Abstract excerpt
PURPOSE: Epidemiologic evidence indicates that time outdoors reduces the risk of myopia, suggesting a possible role for vitamin D. This case-control study was conducted to determine whether single-nucleotide polymorphisms (SNPs) within VDR at 12q13.11 and GC at 4q12-13 are associated with myopia. METHODS: The primary analysis was conducted on 81 white adult control subjects between 18 and 50 years of age with a...
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