Article
Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations.
The Journal of nutrition - 1 Jan 2013
Engelman Corinne D, Meyers Kristin J, Iyengar Sudha K, Liu Zhe, Karki Chitra K, Igo Robert P, Truitt Barbara, Robinson Jennifer, Sarto Gloria E, Wallace Robert, Blodi Barbara A, Klein Michael L, Tinker Lesley, LeBlanc Erin S, Jackson Rebecca D, Song Yiqing, Manson JoAnn E, Mares Julie A, Millen Amy E
Abstract excerpt
Vitamin D deficiency {defined by the blood concentration of 25-hydroxyvitamin D [25(OH)D]} has been associated with many adverse health outcomes. Genetic and nongenetic factors account for variation in 25(OH)D, but the role of interactions between these factors is unknown. To assess this, we examined 1204 women of European descent from the Carotenoids in Age-Related Eye Disease Study, an ancillary study of the...
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