Article
rs12512631 on the group specific complement (vitamin D-binding protein GC) implicated in melanoma susceptibility.
PloS one - 1 Jan 2013
Peña-Chilet Maria, Ibarrola-Villava Maider, Martin-González Manuel, Feito Marta, Gomez-Fernandez Cristina, Planelles Dolores, Carretero Gregorio, Lluch Ana, Nagore Eduardo, Ribas Gloria
Abstract excerpt
BACKGROUND: Solar radiation should be avoided in melanoma patients. Nevertheless, this is the main means by which the body produces vitamin D. Evidence suggests a protective role against cancer for vitamin D. Since vitamin D performs its function by binding the receptor encoded by the vitamin D-receptor gene (VDR), most studies have focused on polymorphisms (SNPs) within this gene. However, the gene encoding the...
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