Article
Genetically low vitamin D concentrations and myopic refractive error: a Mendelian randomization study.
International journal of epidemiology - 1 Dec 2017
Cuellar-Partida Gabriel, Williams Katie M, Yazar Seyhan, Guggenheim Jeremy A, Hewitt Alex W, Williams Cathy, Wang Jie Jin, Kho Pik-Fang, Saw Seang Mei, Cheng Ching-Yu, Wong Tien Yin, Aung Tin, Young Terri L, Tideman J Willem L, Jonas Jost B, Mitchell Paul, Wojciechowski Robert, Stambolian Dwight, Hysi Pirro, Hammond Christopher J, Mackey David A, Lucas Robyn M, MacGregor Stuart
Abstract excerpt
Background: Myopia prevalence has increased in the past 20 years, with many studies linking the increase to reduced time spent outdoors. A number of recent observational studies have shown an inverse association between vitamin D [25(OH)D] serum levels and myopia. However, in such studies it is difficult to separate the effects of time outdoors and vitamin D levels. In this work we use Mendelian randomization...
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