Article
Codon usage variability determines the correlation between proteome and transcriptome fold changes.
BMC systems biology - 25 Feb 2011
Olivares-Hernández Roberto, Bordel Sergio, Nielsen Jens
Abstract excerpt
BACKGROUND: The availability of high throughput experimental methods has made possible to observe the relationships between proteome and transcriptome. The protein abundances show a positive but weak correlation with the concentrations of their cognate mRNAs. This weak correlation implies that there are other crucial effects involved in the regulation of protein translation, different from the sole availability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
