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Article

Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.

Human genetics - 1 Jan 2013

Falah Nadia, McElroy Jude, Snegovskikh Victoria, Lockwood Charles J, Norwitz Errol, Murray Jeffey C, Kuczynski Edward, Menon Ramkumar, Teramo Kari, Muglia Louis J, Morgan Thomas

Abstract excerpt

Preterm birth (PTB) is the leading cause of infant mortality. PTB pathophysiology overlaps with those of adult cardiovascular, immune and metabolic disorders (CIMD), with mechanisms including inflammation, immunotolerance, thrombosis, and nutrient metabolism. Whereas many genetic factors for CIMD have been identified, progress in PTB has lagged. We hypothesized that highly validated genetic risk factors for CIMD...

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Source

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Identifiers

PMID: 22972380
DOI: 10.1007/s00439-012-1223-x
PMCID: PMC3864772

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