Article
A population-specific diabetogenic haplotype HLA-A2,Cw1,B56,DR4,DQ8 is associated with high birthweight in Finnish diabetic families.
Genes and immunity - 1 Apr 2008
Järvinen T M, Harjutsalo V, Kinnunen L, Miettinen M E, Tuomilehto-Wolf E, Tuomilehto J
Abstract excerpt
Children with type 1 diabetes (T1D) susceptibility HLA genotypes are shown to have an increased birthweight. We investigated to what extent T1D-predisposing HLA haplotypes were associated with increased birthweight. A total of 1255 Finnish children comprising those with T1D and their non-diabetic siblings were investigated. A total of 342 children and their non-diabetic parents were HLA genotyped. Birthweight...
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