Article
Rational design of genotyping nanodevice for HPV subtype distinction.
Analytica chimica acta - 2 Oct 2023
Li De Yu, Jiang Yong Jian, Nie Kun Han, Li Jing, Li Yuan Fang, Huang Cheng Zhi, Li Chun Mei
Abstract excerpt
There are more than 200 subtypes of human papillomavirus (HPV), and high-risk HPVs are a leading cause of cervical cancer. Identifying the genotypes of HPV is significant for clinical diagnosis and cancer control. Herein, we used programmable and modified DNA as the backbone to construct fluorescent genotyping nanodevice for HPV subtype distinction. In our strategy, the dye-labeled single-stranded recognize-DNA...
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