Article
Screening for activating EGFR mutations in surgically resected nonsmall cell lung cancer.
The European respiratory journal - 1 Oct 2011
Sriram K B, Tan M E, Savarimuthu S M, Wright C M, Relan V, Stockwell R E, Clarke B E, Duhig E E, Yang I A, Bowman R V, Fong K M
Abstract excerpt
The clinical applicability of screening surgically resected nonsmall cell lung cancer (NSCLC) tumour tissue and serum for activating epidermal growth factor receptor (EGFR) mutation is unknown. Furthermore, the comparative accuracy of inexpensive EGFR mutation tests, mutant-enriched (ME)-PCR and high-resolution melt (HRM) has not been determined. Lung tumour DNA from 522 surgically resected stage I-IV NSCLC and...
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