Article
[Recent progress in iron metabolism and iron-related anemia].
Rinsho byori. The Japanese journal of clinical pathology - 1 Dec 2010
Harigae Hideo
Abstract excerpt
Iron is an essential metal not only in oxygen delivery, but also in cell proliferation and drug metabolism, while it is a very toxic metal producing reactive oxygen species(ROS). In order to avoid the toxicity and shortage of iron, the level of iron is strictly regulated in the body and cells. The central player regulating the amount of iron in the body is hepcidin. Hepcidin inhibits the release of iron from...
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