Article
Duplication and positive selection among hominin-specific PRAME genes.
BMC genomics - 13 Sept 2005
Birtle Zoë, Goodstadt Leo, Ponting Chris
Abstract excerpt
BACKGROUND: The physiological and phenotypic differences between human and chimpanzee are largely specified by our genomic differences. We have been particularly interested in recent duplications in the human genome as examples of relatively large-scale changes to our genome. We performed an in-depth evolutionary analysis of a region of chromosome 1, which is copy number polymorphic among humans, and that...
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