Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

doi:10.1038/nature09884

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

Nature - 24 Mar 2011

Vacic Vladimir, McCarthy Shane, Malhotra Dheeraj, Murray Fiona, Chou Hsun-Hua, Peoples Aine, Makarov Vladimir, Yoon Seungtai, Bhandari Abhishek, Corominas Roser, Iakoucheva Lilia M, Krastoshevsky Olga, Krause Verena, Larach-Walters Verónica, Welsh David K, Craig David, Kelsoe John R, Gershon Elliot S, Leal Suzanne M, Dell Aquila Marie, Morris Derek W, Gill Michael, Corvin Aiden, Insel Paul A, McClellan Jon, King Mary-Claire, Karayiorgou Maria, Levy Deborah L, DeLisi Lynn E, Sebat Jonathan

Abstract excerpt

Rare copy number variants (CNVs) have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large (>500-kilobase) CNVs at several loci, including microdeletions at 1q21.1 (ref. 2), 3q29 (ref. 3), 15q13.3 (ref. 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic AMP

Share to DNA Copy Number Variations

Share to Gene Dosage

Share to Genes, Duplicate

Share to Inheritance Patterns

Share to Reproducibility of Results

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 21346763
DOI: 10.1038/nature09884
PMCID: PMC3351382

Genes

VIPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21346763-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.PMID 21346763Read ↗

Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia.Semantic proximity Read ↗

Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.Semantic proximity Read ↗

Identification of rare mutations of the vasoactive intestinal peptide receptor 2 gene in schizophrenia.Semantic proximity Read ↗

Low-copy repeats at the human VIPR2 gene predispose to recurrent and nonrecurrent rearrangements.Semantic proximity Read ↗

A competitive PCR assay confirms the association of a copy number variation in the VIPR2 gene with schizophrenia in Han Chinese.Semantic proximity Read ↗

Rare chromosomal deletions and duplications increase risk of schizophrenia.Semantic proximity Read ↗

Probing the VIPR2 Microduplication Linkage to Schizophrenia in Animal and Cellular ModelsSemantic proximity Read ↗

Analysis of the association of VIPR2 polymorphisms with susceptibility to schizophrenia.Semantic proximity Read ↗

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.Semantic proximity Read ↗

Characterization of Single Gene Copy Number Variants in Schizophrenia.Semantic proximity Read ↗

Genome-wide Analysis of the Role of Copy Number Variation in Schizophrenia Risk in Chinese.Semantic proximity Read ↗

Does rare matter? Copy number variants at 16p11.2 and the risk of psychosis: a systematic review of literature and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.