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Article

FOXQ1 Regulates Epithelial-Mesenchymal Transition in Human Cancers

23 Feb 2011

Abstract excerpt

Epithelial-mesenchymal transition (EMT) in cancer cells plays a pivotal role in determining metastatic prowess, but knowledge of EMT regulation remains incomplete. In this study, we defined a critical functional role for the Forkhead transcription factor FOXQ1 in regulating EMT in breast cancer cells. FOXQ1 expression was correlated with high-grade basal-like breast cancers and was associated with poor clinical...

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PMID: 21346143
DOI: 10.1158/0008-5472.can-10-2787

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