Article
Genetic variants in miRNAs predict bladder cancer risk and recurrence.
Cancer research - 1 Dec 2012
Wang Meilin, Chu Haiyan, Li Pu, Yuan Lin, Fu Guangbo, Ma Lan, Shi Danni, Zhong Dongyan, Tong Na, Qin Chao, Yin Changjun, Zhang Zhengdong
Abstract excerpt
miRNAs play important roles in numerous cellular processes, including development, proliferation, apoptosis, and carcinogenesis. Because altered expression and function of miRNAs has been observed in bladder cancer, we investigated whether genetic variations in miRNAs are associated with bladder cancer risk and prognosis. Using bioinformatics tools, we selected five single-nucleotide polymorphisms located in...
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