Article
Genetic variation in microRNA genes and prostate cancer risk in North Indian population.
Molecular biology reports - 1 Mar 2011
George Ginu P, Gangwar Ruchika, Mandal Raju K, Sankhwar Satya N, Mittal Rama D
Abstract excerpt
Recent evidence indicates the involvement of microRNAs (miRNAs), in cell growth control, differentiation, and apoptosis, thus playing a role in tumorigenesis. Single-nucleotide polymorphisms (SNPs) located at miRNA-binding sites (miRNA-binding SNPs) are likely to affect the expression of the miRNA target and may contribute to the susceptibility of humans to common diseases. We genotyped SNPs hsa-mir196a2...
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