Article
Identification of ACOX2 as a shared genetic risk factor for preeclampsia and cardiovascular disease.
European journal of human genetics : EJHG - 1 Jul 2011
Johansson Asa, Curran Joanne E, Johnson Matthew P, Freed Katy A, Fenstad Mona H, Bjørge Line, Eide Irina P, Carless Melanie A, Rainwater David L, Goring Harald H H, Austgulen Rigmor, Moses Eric K, Blangero John
Abstract excerpt
Preeclampsia (PE) is a serious complication of pregnancy, which is highly correlated with later life cardiovascular disease (CVD). Many risk factors are common for both diseases, but the contribution of shared genes remains to be determined. In this study, we used an integrative strategy to assess lipid traits as risk factors for PE and CVD by whole genome transcriptional profiling performed on Norwegian decidua...
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