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Article

Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes.

PloS one - 1 Jan 2015

Yong Hannah E J, Melton Phillip E, Johnson Matthew P, Freed Katy A, Kalionis Bill, Murthi Padma, Brennecke Shaun P, Keogh Rosemary J, Moses Eric K

Abstract excerpt

BACKGROUND: Preeclampsia (PE) is a serious hypertensive pregnancy disorder with a significant genetic component. Numerous genetic studies, including our own, have yielded many susceptibility genes from distinct functional groups. Additionally, transcriptome profiling of tissues at the maternal-fetal interface has likewise yielded many differentially expressed genes. Often there is little overlap between these two...

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Source

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Identifiers

PMID: 26010865
DOI: 10.1371/journal.pone.0128230
PMCID: PMC4444079

Genes

ACVR1
AGT
ERAP1
ERAP2
IFNG
INHA
INHBA
INHBB
LNPEP
SERPINE1
TGFB1
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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