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Article

The antigenic drift molecular basis of the H5N1 influenza viruses in a novel branch of clade 2.3.4.

Veterinary microbiology - 25 Jun 2014

Zhong Lei, Zhao Qingqing, Zhao Kunkun, Wang Xiaoquan, Zhao Guo, Li Qunhui, Gu Min, Peng Daxin, Liu Xiufan

Abstract excerpt

H5N1 subtype influenza A virus has evolved into many HA clades since late 1990 s. Six circulating H5N1 influenza viruses clustered to a novel branch in clade 2.3.4 and could escape vaccine protection, indicating their antigenic drift. Eleven amino acids substitutions in three antigenic sites of the hemagglutinin of these isolates were found when compared with the hemagglutinin of the primary viruses in clade...

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Identifiers

PMID: 24745625
DOI: 10.1016/j.vetmic.2014.02.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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