Article
Genome-wide gene expression profiling of formalin-fixed paraffin-embedded breast cancer core biopsies using microarrays.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Feb 2011
Budczies Jan, Weichert Wilko, Noske Aurelia, Müller Berit Maria, Weller Claudia, Wittenberger Timo, Hofmann Hans-Peter, Dietel Manfred, Denkert Carsten, Gekeler Volker
Abstract excerpt
The routine workflow for invasive cancer diagnostics includes biopsy processing by formalin fixation and paraffin embedding. It has been shown only recently that this kind of sample can be used for gene expression analysis with microarrays. To support this view, the authors conducted a microarray study using formalin-fixed paraffin-embedded (FFPE) core needle biopsies from breast cancers. Typically, for the...
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