Article
Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression.
Clinical chemistry - 1 Dec 2010
Hennig Guido, Gehrmann Mathias, Stropp Udo, Brauch Hiltrud, Fritz Peter, Eichelbaum Michel, Schwab Matthias, Schroth Werner
Abstract excerpt
BACKGROUND: There is an increasing need for the identification of both DNA and RNA biomarkers from pathodiagnostic formalin-fixed paraffin-embedded (FFPE) tissue samples for the exploration of individualized therapy strategies in cancer. We investigated a fully automated, xylene-free nucleic acid...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.