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Increased oxidative DNA damage in lean normoglycemic offspring of type 2 diabetic patients.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Sept 2011

Zengi A, Ercan G, Caglayan O, Tamsel S, Karadeniz M, Simsir I, Harman E, Kahraman C, Orman M, Cetinkalp S, Ozgen G

Abstract excerpt

OBJECTIVE: Several studies have shown increased oxidative stress in patients with pre-diabetes and newly diagnosed Type 2 diabetes mellitus (T2DM). It has been proposed that oxidative stress initiates insulin resistance in genetically predisposed individuals. The aim of this study was to evaluate the markers of oxidative stress in the offspring of patients with T2DM. MATERIAL AND METHODS: We examined 60 lean...

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Blood Glucose
8-Hydroxy-2'-Deoxyguanosine
Deoxyguanosine
Glucose Tolerance Test
Parents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prediabetic State

Sulfhydryl Compounds

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PMID: 21472659
DOI: 10.1055/s-0031-1275289

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