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Article

The Polycomb group protein CRAMPED is involved with TRF2 in the activation of the histone H1 gene.

Chromosoma - 1 Jun 2011

Gibert Jean-Michel, Karch François

Abstract excerpt

CRAMPED (CRM), conserved from plants to animals, was previously characterized genetically as a repressive factor involved in the formation of facultative and constitutive heterochromatin (Polycomb silencing, position effect variegation). We show that crm is dynamically regulated during replication and identify the Histone gene cluster (His-C) as a major CRM target. Surprisingly, CRM is specifically required for...

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Identifiers

PMID: 21336627
DOI: 10.1007/s00412-011-0312-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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